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Response Genetics,Inc. (RGI) was founded in 1999 to leverage breakthrough, patented technology from USC for the “extraction of genetic information from formalin-fixed, paraffin-embedded clinical trial samples.” Until that time, RNA was only available from fresh frozen specimens; it was not possible to extract meaningful genetic information from diagnostic specimens fixed and stored in paraffin before the discovery of RGI's patented method.
Our success in developing this technology allows us to deliver tangible benefits to pharmaceutical companies and to create new platforms to support the industry with more efficient, cost-effective analysis of clinical trial samples, leading to the development of more “personalized” patient therapies.
Tom Bologna joined Response Genetics as our Chief Executive Officer in December 2011. From April 2006 until joining Response Genetics, Mr. Bologna served as President and Chief Executive Officer of Orchid Cellmark, Inc., a NASDAQ-listed corporation and a leading service provider of DNA identity testing. Prior to joining Orchid Cellmark, Mr. Bologna was President, Chief Executive Officer and a member of the board of the venture-backed Quorex Pharmaceuticals, Inc., where he orchestrated a successful sale to Pfizer Inc. Prior to leading Quorex, Mr. Bologna was Chairman of the Board, President and Chief Executive Officer of Ostex International, Inc., a NASDAQ-listed biotechnology company that developed and commercialized disease management products with a focus on osteoporosis. Mr. Bologna oversaw the sale of Ostex to Alere Inc. (formally Inverness Medical Innovations).
Mr. Bologna.s prior experience includes serving as President and Chief Executive Officer of Scriptgen Pharmaceuticals, Inc., a Boston biotechnology start-up company. Before leading Scriptgen, Mr. Bologna was Chairman of the Board, President and Chief Executive Officer of Gen-Probe, Incorporated, a global leader in the development, manufacture and marketing of molecular diagnostic products. He led Gen-Probe through its initial public offering on NASDAQ and oversaw its subsequent sale to Chugai Pharmaceutical Co., Ltd. Mr. Bologna has also held senior-level positions with Becton Dickinson & Company and Warner-Lambert Company (Pfizer), two leading Fortune 500 healthcare companies. Mr. Bologna served as President of the Becton Dickinson Diagnostic Instrument Systems Division and as a Vice President of the Warner-Lambert Company .
Mr. O’Toole joined Response Genetics in May of 2010. He most recently served as Executive Vice President and Chief Financial Officer of Abraxis Bioscience, LLC. Prior to his experience with Abraxis, Mr. O’Toole spent twenty four years in public accounting. Starting in 1984 he was with Arthur Andersen for eight years and then spent sixteen years with Deloitte & Touche serving as Partner on many large multinational corporations. The last ten years in public accounting, his industry focus was in Life Science and Biotech. During his career in public accounting, Mr. O’Toole spent two years in Tokyo, Japan and two years in Paris, France.
Mr. O’Toole received a B.S. in Accounting from the University of Arizona.
Denise McNairn joined Response Genetics as our Vice President and General Counsel in February 2007. Prior to joining the business, from 2001 to 2007, Ms. McNairn was an attorney at Kenyon & Kenyon LLP. Her legal experience covers all areas of intellectual property, including patent and trademark litigation, patent prosecution, and licensing. Ms. McNairn's patent litigation experience is focused in the life sciences, including pharmaceuticals, biotechnology and devices.
Prior to Kenyon & Kenyon, Ms. McNairn worked as a Technology Transfer Specialist at the National Cancer Institute Technology Transfer Branch, where she began her career in drafting and negotiating transactional agreements. Prior to beginning her legal career, Ms. McNairn worked a number of years in the biotechnology field and was an infectious disease researcher.
Ms. McNairn received her B.S. from Virginia Polytechnic Institute and State University, an M.S. from Johns Hopkins University and her J.D. from the University of Maryland School of Law.